The main energy substrate of the brain is glucose, and—to a lesser . through sequestration into membrane-engulfed autophagosomes. These.
Nat Rev Drug Discov. Jan;12(1) doi: /nrd Epub Dec Kynurenines in the CNS: recent advances and new questions.
The in vivo disposition of kynurenine in the brain depends on the cellular localization, intracellular compartmentalization and kinetic characteristics of these two.
Doxycycline reduces mortality and injury to the brain and cochlea in .. invading bacterium, which then becomes engulfed by the cell membrane and.
As noted earlier, the significance for the host of IDO-1 induction in the endothelium is unclear. The kynurenine pathway and parasitic infections that affect CNS.
the brain. The kynurenine pathway is under immunological control and can be induced Astrocytes tightly engulf the synapse in an interaction termed "the.
Shunting of tryptophan metabolism toward kynurenine pathway (KP) and In addition, a volumetric analysis of brain structures of the limbic system was pathogens, phagocytes such as macrophages that engulf microbes, and toll-like .